Episode 7 - Hot Dog Buns, Hard Lines and Floppy Bits

After a hard day's work, sometimes you want to just kick your feet back and relax. Unfortunately, sometimes your CD8 T-cells want the same thing, even though they don't have feet. During chronic viral infections, T-cells get exhausted, and this fact has enormous implications for human health. We discuss what killer T-cells are, how and why they get exhausted, and new research that points towards potential therapy for everything from HIV to cancer.

Links:

• The paper: Restoring function in exhausted CD8 T cells during chronic viral infection